Interleukin 24 (IL24) Antibody
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935106861
info@markelab.com
Precio
357.5€ (100 µg)
Antibody anti-IL24
proveedor
Abbexareference
abx037984Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Rabbit Polyclonal against the IL24 protein.
Background
Interleukin 24 (IL24) is a cytokine belonging to the IL-10 family, which includes other related cytokines such as IL-10, IL-19, IL-20, IL-22, and IL-26. IL-24 was first identified as melanoma differentiation-associated gene-7 (mda-7), due to its expression being upregulated during the process of melanoma cell differentiation. It plays a key role in immune regulation, cell survival, apoptosis, and the modulation of inflammatory responses. IL-24 is unique in its ability to induce apoptosis selectively in cancer cells without affecting normal cells, making it a promising therapeutic target for cancer treatment. IL-24 is produced by a variety of immune cells, including macrophages, monocytes, and T-cells, and is involved in both immune modulation and inflammation. Its expression can be triggered by pro-inflammatory signals, such as TNF-α and IFN-γ
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Interleukin 24 (IL24)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Lyophilized
tested applications
ELISA, WB
purification
Purified by Protein A/G column chromatography.
recommended dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
buffer
Prior to lyophilization: 0.02% NaN3.
size 1
100 µg
size 2
1 mg
storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
or code
IL24
dry ice
No
availability
Shipped within 7-15 working days.
alias
C49A,FISP,MDA7,MOB5,ST16,IL10B,Melanoma differentiation-associated gene 7 protein,Suppression of tumorigenicity 16 protein
note
Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. -
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