Interleukin 24 (IL24) Antibody
299€ (100 µl)
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Name
Interleukin 24 (IL24) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx101198
Tested Applications
WB
Description
Polyclonal Antibody to Interleukin 24 (IL24).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 24 (IL24) Immunogen: IL24 (Gln29-Leu183) |
| Host | Rabbit |
| Reactivity | Rat |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC (Predicted): 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9JI24 |
| Alias | C49A,FISP,MDA7,MOB5,ST16,IL10B,Melanoma differentiation-associated gene 7 protein,Suppression of tumorigenicity 16 protein |
| Background | Antibody anti-IL24 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Interleukin 24 (IL24) is a cytokine belonging to the IL-10 family, which includes other related cytokines such as IL-10, IL-19, IL-20, IL-22, and IL-26. IL-24 was first identified as melanoma differentiation-associated gene-7 (mda-7), due to its expression being upregulated during the process of melanoma cell differentiation. It plays a key role in immune regulation, cell survival, apoptosis, and the modulation of inflammatory responses. IL-24 is unique in its ability to induce apoptosis selectively in cancer cells without affecting normal cells, making it a promising therapeutic target for cancer treatment. IL-24 is produced by a variety of immune cells, including macrophages, monocytes, and T-cells, and is involved in both immune modulation and inflammation. Its expression can be triggered by pro-inflammatory signals, such as TNF-α and IFN-γ
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