Interleukin 2 (IL2) Antibody

383.5€ (100 µl)
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name
Interleukin 2 (IL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx010976
tested applications
ELISA
Description
IL-2: interleukin-2. Entrez Protein NP000577. It is a 17.6kDa secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Interleukin 2 (IL2) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG1 |
Purification | Unpurified ascites. |
Size 1 | 100 µl |
Form | Liquid |
Tested Applications | ELISA |
Buffer | Ascitic fluid containing 0.03% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P60568 |
Gene ID | 3558 |
OMIM | 147680 |
Alias | IL-2,TCGF,lymphokine,T-cell growth factor |
Background | Antibody anti-IL2 |
Status | RUO |
Note | Concentration: Not determined. - |
Descripción
Interleukin-2 (IL2) is a key cytokine that plays a crucial role in the immune system, particularly in the activation and regulation of immune responses. First discovered in 1976, IL-2 was initially referred to as "T-cell growth factor" due to its role in the proliferation of T cells, a vital component of the immune system. IL-2 has since become recognized as one of the most important cytokines for maintaining immune homeostasis and enhancing the activity of immune cells, including natural killer (NK) cells, B cells, and T cells. Its role in immune modulation has significant implications in both health and disease, including cancer, autoimmune diseases, and infections.
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