Interleukin 2 (IL2) Antibody
195€ (20 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Interleukin 2 (IL2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx000679
Tested Applications
ELISA, WB
Description
IL2 Antibody is a Rabbit Polyclonal antibody against IL2. The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 2 (IL2) Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-153 of human IL2. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 18 kDa Observed MW: 15-20 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P60568 |
| Gene ID | 3558 |
| NCBI Accession | NP_000577.2 |
| Alias | IL-2,TCGF,lymphokine,T-cell growth factor |
| Background | Antibody anti-IL2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Interleukin-2 (IL2) is a key cytokine that plays a crucial role in the immune system, particularly in the activation and regulation of immune responses. First discovered in 1976, IL-2 was initially referred to as "T-cell growth factor" due to its role in the proliferation of T cells, a vital component of the immune system. IL-2 has since become recognized as one of the most important cytokines for maintaining immune homeostasis and enhancing the activity of immune cells, including natural killer (NK) cells, B cells, and T cells. Its role in immune modulation has significant implications in both health and disease, including cancer, autoimmune diseases, and infections.
Productos relacionados
Interleukin 2 (IL2) Antibody
IL2 Antibody is a Rabbit Polyclonal antibody against IL2. The protein encoded by this gene is a secreted cytokine that i…
Ver producto
Interleukin 2 (IL2) Antibody
IL-2: interleukin-2. Entrez Protein NP000577. It is a 17.6kDa secreted cytokine that is important for the proliferation …
Ver producto
Interleukin 2 (IL2) Antibody
Interleukin 2 Antibody is a Mouse monoclonal antibody for cytokines and growth factors against Interleukin 2. This produ…
Ver producto