Interleukin 16 (IL16) Antibody
377€ (100 µg)
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Name
Interleukin 16 (IL16) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx146975
Tested Applications
ELISA, WB, IHC
Description
Interleukin 16 (IL16) Antibody is a Rabbit Polyclonal antibody for the detection of IL-16.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 16 (IL16) Immunogen: interleukin 16(lymphocyte chemoattractant factor) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 59, 66, 141 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q14005 |
| Gene ID | 3603 |
| OMIM | 603035 |
| Alias | LCF,NIL16,PRIL16,prIL-16,Pro-interleukin-16,Lymphocyte chemoattractant factor |
| Background | Antibody anti-IL16 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Interleukin 16 (IL16) is a pro-inflammatory cytokine that plays a critical role in immune system regulation, particularly in the recruitment and activation of immune cells such as CD4+ T cells, eosinophils, monocytes, and dendritic cells. It functions as a chemoattractant, orchestrating immune cell migration to sites of inflammation and infection, and thus facilitating the body's defense mechanisms. IL-16 is unique in that it acts primarily through its interaction with the CD4 receptor, which is widely expressed on various immune cells. It also modulates the activity of these cells, influencing both innate and adaptive immune responses. Originally identified for its ability to attract CD4+ T cells, IL-16 was subsequently found to have broader roles, including immune cell activation, modulation of cytokine production, and inhibition of viral replication. This has made IL-16 an important factor in various inflammatory conditions, such as asthma, allergic responses, and autoimmune diseases.
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