Interleukin 16 (IL16) Antibody
383.5€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Interleukin 16 (IL16) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx011003
tested applications
ELISA
Description
Interleukin-16, also known as lymphocyte chemoattractant factor (LCF), is a chemotactic cytokine that stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils through binding to the CD4 receptor. IL-16 induces human T-lymphocyte expression of interleukin 2 receptor and upregurates major histocompatibility complex II molecules on resting human T lymphocyte. It is able to render CD4+ T cells unresponsive to TCR/CD3 stimuli. Moreover, IL-16 inhibits the replication of T cell and monocyte tropic HIV strains in vitro.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interleukin 16 (IL16) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q14005 |
| Gene ID | 3603 |
| OMIM | 603035 |
| Alias | LCF,NIL16,PRIL16,prIL-16,Pro-interleukin-16,Lymphocyte chemoattractant factor |
| Background | Antibody anti-IL16 |
| Status | RUO |
| Note | Concentration: Not determined. - |
Descripción
Interleukin 16 (IL16) is a pro-inflammatory cytokine that plays a critical role in immune system regulation, particularly in the recruitment and activation of immune cells such as CD4+ T cells, eosinophils, monocytes, and dendritic cells. It functions as a chemoattractant, orchestrating immune cell migration to sites of inflammation and infection, and thus facilitating the body's defense mechanisms. IL-16 is unique in that it acts primarily through its interaction with the CD4 receptor, which is widely expressed on various immune cells. It also modulates the activity of these cells, influencing both innate and adaptive immune responses. Originally identified for its ability to attract CD4+ T cells, IL-16 was subsequently found to have broader roles, including immune cell activation, modulation of cytokine production, and inhibition of viral replication. This has made IL-16 an important factor in various inflammatory conditions, such as asthma, allergic responses, and autoimmune diseases.
Related Products
Chicken IL-16 (Interleukin 16) ELISA Kit
Ver Producto
Human IL-16 (Interleukin 16) ELISA Kit
Ver Producto