Interferon Alpha 5 (IFNA5) Antibody
292.5€ (80 µl)
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935106861
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name
Interferon Alpha 5 (IFNA5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx030316
tested applications
ELISA, WB
Description
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interferon Alpha 5 (IFNA5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01569 |
| Alias | INA5,INFA5,leIF G,IFN-alphaG,IFN-alpha-5,Interferon alpha-61,Interferon alpha-G |
| Background | Antibody anti-IFNA5 |
| Status | RUO |
Descripción
Interferon Alpha 5 (IFNA5) is a member of the type I interferon family and plays a vital role in innate and adaptive immune responses. IFNA5 is secreted by immune cells like dendritic cells, macrophages, and lymphocytes in response to viral infections, double-stranded RNA, or other pathogen-associated molecular patterns (PAMPs). Once released, IFNA5 binds to the interferon-alpha/beta receptor (IFNAR), initiating a signaling cascade through the JAK-STAT pathway. This cascade induces the transcription of interferon-stimulated genes, which activate antiviral, antiproliferative, and immunomodulatory mechanisms. These effects include inhibition of viral replication, increased antigen presentation, and activation of natural killer (NK) cells and cytotoxic T lymphocytes. While not as widely studied as IFNA2, IFNA5 may have tissue-specific or pathogen-specific roles, contributing to its nuanced function within the immune system.
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