Intelectin 2 (ITLN2) Antibody

Este producto es parte de ITLN - Intelectin (Omentin)
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357.5€ (100 µg)

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935106861
info@markelab.com
name
Intelectin 2 (ITLN2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx037210
tested applications
ELISA, WB, IHC

Description

Rabbit Polyclonal against the ITLN2 protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Intelectin 2 (ITLN2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/20000 - 1/80000, WB: 1/1000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by antigen affinity column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB, IHC
Buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
HL2,HL-2
Background
Antibody anti-ITLN2
Status
RUO
Note
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml. -

Descripción

ITLN2 is a closely related intelectin family protein sharing structural and functional similarities with ITLN1 It is secreted and primarily expressed in the gastrointestinal tract and other epithelial tissues ITLN2 participates in innate immunity by recognizing and binding to microbial components, particularly carbohydrate moieties on pathogenic bacteria and fungi It enhances microbial clearance by facilitating phagocytosis and immune activation ITLN2 expression is regulated during infection and inflammation, playing a critical role in host defense mechanisms Unlike ITLN1, ITLN2 appears to have a more restricted expression pattern and is less associated with metabolic regulation, focusing on immune surveillance in mucosal surfaces Dysregulation of ITLN2 may impair barrier immunity and has been implicated in gut inflammation and intestinal disorders, where its deficiency could increase susceptibility to infections and inflammatory bowel diseases ITLN2 represents a valuable component of epithelial defense mechanisms against microbial challenges

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