Intelectin 2 (ITLN2) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Intelectin 2 (ITLN2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx027537
tested applications
ELISA, WB
Description
ITLN2 may play a role in the defense system against pathogens (By similarity).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Intelectin 2 (ITLN2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8WWU7 |
| Gene ID | 142683 |
| OMIM | 609874 |
| Alias | HL2,HL-2 |
| Background | Antibody anti-ITLN2 |
| Status | RUO |
Descripción
ITLN2 is a closely related intelectin family protein sharing structural and functional similarities with ITLN1 It is secreted and primarily expressed in the gastrointestinal tract and other epithelial tissues ITLN2 participates in innate immunity by recognizing and binding to microbial components, particularly carbohydrate moieties on pathogenic bacteria and fungi It enhances microbial clearance by facilitating phagocytosis and immune activation ITLN2 expression is regulated during infection and inflammation, playing a critical role in host defense mechanisms Unlike ITLN1, ITLN2 appears to have a more restricted expression pattern and is less associated with metabolic regulation, focusing on immune surveillance in mucosal surfaces Dysregulation of ITLN2 may impair barrier immunity and has been implicated in gut inflammation and intestinal disorders, where its deficiency could increase susceptibility to infections and inflammatory bowel diseases ITLN2 represents a valuable component of epithelial defense mechanisms against microbial challenges
Related Products
Human ITLN2 (Intelectin 2) ELISA Kit
Ver Producto
Recombinant Human ITLN2
Ver Producto
Intelectin 2 (ITLN2) Antibody
ITLN2 may play a role in the defense system against pathogens (By similarity).
Ver Producto