Insulin Receptor (INSR) Antibody
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Description
Insulin Receptor (INSR) Antibody is a Rabbit polyclonal antibody for the detection of Human Insulin Receptor (INSR).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Insulin Receptor (INSR) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P06213 |
| Gene ID | 3643 |
| NCBI Accession | NP_000199.2 |
| Alias | HHF5,CD220,IR |
| Background | Antibody anti-INSR |
| Status | RUO |
Descripción
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Human INSR (Insulin receptor) ELISA Kit
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INSR antibody
This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.
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