Immunoglobulin Superfamily Member 11 (IGSF11) Antibody
364€ (100 µg)
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935106861
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name
Immunoglobulin Superfamily Member 11 (IGSF11) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx234190
tested applications
ELISA, WB, IHC
Description
IGSF11 Antibody is a Rabbit Polyclonal against IGSF11.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Immunoglobulin Superfamily Member 11 (IGSF11) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5DX21 |
| Gene ID | 152404 |
| OMIM | 608351 |
| Alias | CT119,VSIG3,BTIGSF,Igsf13,BT-IgSF,CXADRL1,V-set and immunoglobulin domain-containing protein ,Brain and testis-specific immunoglobulin superfamily protein |
| Background | Antibody anti-IGSF11 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
IGSF11 is a transmembrane adhesion molecule primarily expressed in the brain, where it is localized at excitatory synapses. It contains Ig-like domains that mediate homophilic and heterophilic interactions with other synaptic proteins, influencing synaptic organization and plasticity. IGSF11 is essential for the stabilization of AMPA receptors, which are critical for synaptic transmission and long-term potentiation (LTP). Dysregulation of IGSF11 has been implicated in neurodevelopmental disorders such as autism spectrum disorders (ASD) and schizophrenia. It also plays a role in tumor biology, where it modulates cancer cell adhesion and migration in certain cancers.
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