Human Vasoactive Intestinal Peptide Receptor 1 (VIPR1) CLIA Kit
845€ (96 tests)
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name
Human Vasoactive Intestinal Peptide Receptor 1 (VIPR1) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx493782
tested applications
CLIA
Description
Human Vasoactive Intestinal Peptide Receptor 1 (VIPR1) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Vasoactive Intestinal Peptide Receptor 1 (VIPR1) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | VIPR1,Pituitary adenylate cyclase-activating polypeptide type II receptor,PACAP type II receptor,PACAP-R-2,PACAP-R2,VPAC1 |
| Background | CLIA Kits VIPR1 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
VIPR1 is a G protein-coupled receptor activated by vasoactive intestinal peptide (VIP), a neuropeptide involved in regulating smooth muscle relaxation, vasodilation, and neurotransmission. VIPR1 couples to Gs proteins, stimulating adenylate cyclase and increasing cAMP levels, leading to relaxation of smooth muscle cells, dilation of blood vessels, and modulation of gastrointestinal motility. VIPR1 is primarily expressed in the smooth muscle of the gastrointestinal tract, blood vessels, and the central nervous system, where it plays a role in regulating vascular tone, intestinal motility, and neurotransmitter release. VIP has a significant role in regulating inflammation and immune responses, and VIPR1 signaling is involved in modulating immune cell functions. Dysregulation of VIPR1 signaling has been implicated in inflammatory diseases, gastrointestinal disorders, and cardiovascular diseases. Agonists targeting VIPR1 are being investigated for their potential to treat diseases involving smooth muscle contraction and inflammation, such as asthma, irritable bowel syndrome (IBS), and hypertension.
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