Human V-Set And Immunoglobulin Domain Containing Protein 2 (VSIG2) Protein

Product specifications

Proteins and Peptides

V-Set And Immunoglobulin Domain Containing Protein 2 (VSIG2)

E. coli

Human

Unconjugated

Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Please enquire.
Tag: N-terminal His tag

Recombinant

> 90%

1 mg

5 mg

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.

WB, SDS-PAGE

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

Shipped within 1-2 months.

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

No

CTH,CTXL,Cortical thymocyte-like protein,CT-like protein

Protein VSIG2

RUO

This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

V-set and immunoglobulin domain containing 2 (VSIG2) is a member of the immunoglobulin superfamily and is primarily expressed in epithelial cells across various tissues, particularly in the gastrointestinal and urogenital tracts. This protein is involved in cell adhesion and potentially plays roles in epithelial cell organization and barrier formation. It has been suggested to function as a mediator of intercellular communication and contribute to tissue integrity by maintaining cell polarity and suppressing excessive cell migration. VSIG2 is also of interest in cancer research due to its altered expression in various malignancies, such as colorectal and gastric cancers, where it is hypothesized to influence tumor progression and metastasis. Furthermore, VSIG2 may have immunomodulatory roles, interacting with immune cells to regulate inflammatory responses and maintaining epithelial-immune system homeostasis. Current studies explore its potential as a biomarker for cancer prognosis and a target for therapeutic interventions aimed at modulating tumor-immune interactions. The exact mechanisms of VSIG2 signaling remain an area of active investigation, particularly in its roles in epithelial tissue maintenance and cancer biology.

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