Human UNC5B(Netrin Receptor UNC5B) ELISA Kit

Este producto es parte de UNC5 - unc-5 netrin receptor
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935106861
info@markelab.com
name
Human UNC5B(Netrin Receptor UNC5B) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH4330

Documents del producto

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Data sheet

Product specifications

CategoryELISA Kits
Reactivityhuman
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich ELISA, Double Antibody
Test Range0.313-20ng/ml
Size 196T
Sample TypeSerum,Plasma,Tissue homogenates,Other biological fluids
AvailabilityShipped within 10-14 working days.
Storage2-8 °C for 6 months
UniProt IDQ8IZJ1
AliasUNC5H2,p53RDL1,Protein unc-5 homolog 2,Protein unc-5 homolog B,p53-regulated receptor for death and life protein 1,Netrin receptor UNC5B
BackgroundElisa Kits UNC5B
StatusRUO

unc-5 netrin receptor B (UNC5B) acts as a receptor for netrin-1, orchestrating key cellular processes like axonal guidance and vascular development. UNC5B ensures proper vascular and neuronal organization by transmitting repellent cues that direct cellular movements. In endothelial cells, UNC5B is vital for angiogenesis, controlling endothelial migration and sprouting. Beyond developmental contexts, UNC5B is implicated in tumor suppression through apoptosis activation in netrin-1’s absence, akin to its role as a dependence receptor. Dysregulation of UNC5B has been linked to pathological angiogenesis and malignancies, highlighting its dual importance in both developmental and pathological processes.

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