Human UBX Domain-Containing Protein 1 (UBXN1) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human UBX Domain-Containing Protein 1 (UBXN1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx384100
tested applications
ELISA
Description
Human UBX Domain-Containing Protein 1 (UBXN1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human UBXN1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | UBX Domain-Containing Protein 1 (UBXN1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.07 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q04323 |
| Gene ID | 51035 |
| OMIM | 616378 |
| Alias | 2B28,SAKS1,UBXD10,SAPK substrate protein 1,UBA/UBX 33.3 kDa protein |
| Background | Elisa kits for UBXN1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
UBX domain protein 1 (UBXN1) is a ubiquitin regulatory protein containing a UBX domain, which enables its interaction with p97/VCP, a key ATPase involved in protein degradation and cellular quality control UBXN1 functions as a cofactor for p97, participating in the extraction and degradation of misfolded proteins during endoplasmic reticulum-associated degradation (ERAD) It regulates protein homeostasis by linking p97 to the ubiquitin-proteasome system and autophagy pathways UBXN1 is also involved in DNA damage repair, where it regulates protein turnover at replication forks and facilitates chromatin remodeling Dysregulation of UBXN1 impairs protein clearance, contributing to neurodegenerative diseases such as Alzheimer’s and Parkinson’s, where protein aggregates accumulate in neurons Emerging studies also connect UBXN1 to cancer biology, as it influences protein turnover in tumor cells and regulates apoptosis Its role in maintaining proteostasis and cellular stress responses underscores its importance in cellular quality control mechanisms
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