Human Tyrosine Phosphatase Alpha / LRP (PTPRA) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for PTPRA
proveedor
Abbexareference
abx514442Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Tyrosine Phosphatase Alpha / LRP (PTPRA) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Tyrosine Phosphatase Alpha / LRP (PTPRA) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
PTPRA is a receptor-like protein tyrosine phosphatase involved in dephosphorylating tyrosine residues in target proteins to regulate cellular signaling pathways. Structurally, it has an extracellular domain, a transmembrane region, and two intracellular phosphatase domains, with the first domain being enzymatically active. PTPRA is expressed ubiquitously, with high levels in brain and muscle tissues. It activates Src family kinases by dephosphorylating inhibitory phosphotyrosines, influencing cell proliferation, adhesion, and migration. PTPRA plays significant roles in neuronal signaling, integrin-mediated cell adhesion, and oncogenic processes. Dysregulation is associated with cancers and neurological disorders.
Características del producto
category
ELISA Kits
immunogen target
Tyrosine Phosphatase Alpha / LRP (PTPRA)
reactivity
Human
test range
0.312 ng/ml - 20 ng/ml
sensitivity
0.084 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
LRP,HLPR,PTPA,HEPTP,HPTPA,RPTPA,PTPRL2,HPTPalpha,R-PTP-alpha,Protein-tyrosine phosphatase alpha,Receptor-type tyrosine-protein phosphatase alpha
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
PTPRA
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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