Protein Tyrosine Phosphatase Receptor Type A (PTPRA) Antibody
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935106861
info@markelab.com
Precio
195€ (20 µl)
Antibody anti-PTPRA
proveedor
Abbexareference
abx126438Tested Applications
ELISA, WBreactivity
Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
PTPRA Antibody is a Rabbit Polyclonal against PTPRA.
Background
PTPRA is a receptor-like protein tyrosine phosphatase involved in dephosphorylating tyrosine residues in target proteins to regulate cellular signaling pathways. Structurally, it has an extracellular domain, a transmembrane region, and two intracellular phosphatase domains, with the first domain being enzymatically active. PTPRA is expressed ubiquitously, with high levels in brain and muscle tissues. It activates Src family kinases by dephosphorylating inhibitory phosphotyrosines, influencing cell proliferation, adhesion, and migration. PTPRA plays significant roles in neuronal signaling, integrin-mediated cell adhesion, and oncogenic processes. Dysregulation is associated with cancers and neurological disorders.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Mouse, Rat
immunogen target
Protein Tyrosine Phosphatase Receptor Type A (PTPRA)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified by affinity chromatography.
recommended dilution
ELISA: 1 µg/ml, WB: 1/1000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
size 1
20 µl
size 2
100 µl
size 3
2 × 100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
PTPRA
dry ice
No
availability
Shipped within 5-10 working days.
alias
LRP,HLPR,PTPA,HEPTP,HPTPA,RPTPA,PTPRL2,HPTPalpha,R-PTP-alpha,Protein-tyrosine phosphatase alpha,Receptor-type tyrosine-protein phosphatase alpha
uniprot id
NCBI accession
NP_543030.1
note
Concentration: > 0.2 mg/ml -
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