Human Tumor Necrosis Factor Receptor Superfamily Member 13B / CD267 (TNFRSF13B) Protein (Active)

Este producto es parte de TNFRSF13B - TNF receptor superfamily member 13B
Human Tumor Necrosis Factor Receptor Superfamily Member 13B / CD267 (TNFRSF13B) Protein (Active)

Pida mas información

935106861

info@markelab.com

Precio

3612.5€ (1 mg)

Protein TNFRSF13B

proveedor

Abbexa

reference

abx655850

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) Protein (Active) is an Active Recombinant Human protein.


Background

TNFRSF13B, also known as TACI (Transmembrane Activator and CAML Interactor), is a critical receptor in the immune system, specifically involved in B cell biology. TNFRSF13B belongs to the tumor necrosis factor receptor superfamily (TNFRSF) and plays an essential role in immune regulation by binding ligands such as APRIL (a proliferation-inducing ligand) and BAFF (B-cell activating factor). These interactions are vital for B cell survival, proliferation, and differentiation, particularly in the context of generating long-lasting immune responses and maintaining immune homeostasis. Mutations in TNFRSF13B have been linked to various immunodeficiency disorders, such as Common Variable Immunodeficiency (CVID) and IgA deficiency. These conditions are associated with impaired antibody production, resulting in increased susceptibility to infections and autoimmune complications. Due to its importance in regulating immune responses, TNFRSF13B is studied intensively as a therapeutic target for both immunodeficiency disorders and autoimmune diseases where B cell activity is dysregulated.

Características del producto

category

Proteins and Peptides


origin

Human


immunogen target

Tumor Necrosis Factor Receptor Superfamily Member 13B / CD267 (TNFRSF13B)


conjugation

Unconjugated


form

Lyophilized


tested applications

WB, SDS-PAGE


size 1

1 mg


size 2

5 mg


expression

Recombinant


purity

> 90%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

TNFRSF13B


dry ice

No


availability

Shipped within 1-2 months.


alias

Tumor necrosis factor receptor superfamily member 13B,CVID,RYZN,TACI,CD267,CVID2,IGAD2,TNFRSF14B,Transmembrane activator and CAML interactor


note

This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.


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reference

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Tested Applications

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reactivity

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