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Human Tumor Necrosis Factor Receptor Superfamily Member 13B / CD267 (TNFRSF13B) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits TNFRSF13B
proveedor
Abbexareference
abx252445Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Tumor Necrosis Factor Receptor Superfamily Member 13B / CD267 (TNFRSF13B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Tumor Necrosis Factor Receptor Superfamily Member 13B / CD267 (TNFRSF13B) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
TNFRSF13B, also known as TACI (Transmembrane Activator and CAML Interactor), is a critical receptor in the immune system, specifically involved in B cell biology. TNFRSF13B belongs to the tumor necrosis factor receptor superfamily (TNFRSF) and plays an essential role in immune regulation by binding ligands such as APRIL (a proliferation-inducing ligand) and BAFF (B-cell activating factor). These interactions are vital for B cell survival, proliferation, and differentiation, particularly in the context of generating long-lasting immune responses and maintaining immune homeostasis. Mutations in TNFRSF13B have been linked to various immunodeficiency disorders, such as Common Variable Immunodeficiency (CVID) and IgA deficiency. These conditions are associated with impaired antibody production, resulting in increased susceptibility to infections and autoimmune complications. Due to its importance in regulating immune responses, TNFRSF13B is studied intensively as a therapeutic target for both immunodeficiency disorders and autoimmune diseases where B cell activity is dysregulated.
Características del producto
category
ELISA Kits
immunogen target
Tumor Necrosis Factor Receptor Superfamily Member 13B / CD267 (TNFRSF13B)
reactivity
Human
test range
0.312 ng/ml - 20 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
Tumor necrosis factor receptor superfamily member 13B,CVID,RYZN,TACI,CD267,CVID2,IGAD2,TNFRSF14B,Transmembrane activator and CAML interactor
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
TNFRSF13B
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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