Human Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14) CLIA Kit

Human Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14) CLIA Kit es un kit CLIA contra el Miembro 14 de la Superfamilia del Ligando del Factor de Necrosis Tumoral (TNFSF14).

Background

TNFSF14, also known as LIGHT (Lymphotoxin-like, exhibits inducible expression, competes with herpes simplex virus glycoprotein D for HVEM, a receptor expressed by T lymphocytes), is a member of the tumor necrosis factor (TNF) superfamily. This ligand is pivotal in immune response modulation and is highly expressed by activated T cells, NK (natural killer) cells, and certain myeloid cells. LIGHT interacts with several receptors, including HVEM (Herpes Virus Entry Mediator), LTβR (Lymphotoxin beta receptor), and DcR3 (Decoy receptor 3), each playing a distinct role in immune signaling pathways. LIGHT’s functions are diverse and are integral to immune cell proliferation, differentiation, survival, and inflammation, with its dysregulation linked to several immune and inflammatory diseases, as well as certain cancers.