Human TRIM33 (tripartite motif-containing 33) QuickTest ELISA Kit

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Product specifications
Category | ELISA Kits |
Reactivity | Human |
Assay Data | 120 minutes |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 31.25-2000pg/ml |
Sensitivity | 18.75pg/ml |
Size 1 | 96T |
Tested Applications | ELISA |
Sample Type | Serum, plasma, cell culture supernatant, cell lysate or tissue lysate, other biological fluid samples |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 12 months |
UniProt ID | Q9UPN9 |
Alias | E3 ubiquitin-protein ligase TRIM33, Ectodermin homolog, RET-fused gene 7 protein, Protein Rfg7, RING-type E3 ubiquitin transferase TRIM33, Transcription intermediary factor 1-gamma, TIF1-gamma, Tripartite motif-containing protein 33, TRIM33, KIAA1113, RFG7, TIF1G |
Background | Elisa kits for TRIM33 |
Status | RUO |
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Human TRIM33 (tripartite motif-containing 33) ELISA Kit
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TRIM33 antibody
Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor(By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade(Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
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