Human TRAF5 (TNF receptor associated factors 5) ELISA Kit
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human TRAF5 (TNF receptor associated factors 5) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH13151
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.313-20ng/ml |
| Sensitivity | 0.188ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | O00463 |
| Alias | TRAF-5,TRAF5, MGC:39780, RNF84, TNF receptor associated factor 5 |
| Background | Elisa kits for TRAF5 |
| Status | RUO |
Background
TRAF5 is a signaling adaptor protein that mediates pathways downstream of TNF receptors (TNFR), CD40, and BAFF-R, activating NF-κB and JNK to regulate inflammation, immune cell activation, and survival. TRAF5 plays a critical role in adaptive immune responses, particularly in T and B cell activation, cytokine production, and lymphoid tissue development. It works redundantly with TRAF2 to promote canonical NF-κB activation, ensuring appropriate immune responses to inflammatory and survival signals. TRAF5 is widely expressed in immune cells and epithelial tissues, where it supports cellular signaling during infections and tissue repair. Dysregulation of TRAF5 contributes to autoimmune diseases and inflammatory conditions, where altered NF-κB signaling enhances cytokine production and immune cell proliferation. Knockout studies reveal defects in lymphocyte activation, impaired cytokine signaling, and altered immune responses, highlighting its importance in immune regulation and inflammatory signaling.
Productos relacionados
Human TNF Receptor Associated Factor 5 (TRAF5) Protein
Human TRAF5 (TRAF5) is a recombinant Human protein expressed in E. coli.…
Ver producto
TNF Receptor Associated Factor 5 (TRAF5) Antibody
Polyclonal Antibody to TRAF5 (TRAF5).…
Ver producto
TNF Receptor-Associated Factor 5 (TRAF5) Antibody
TRAF5 Antibody is a Rabbit Polyclonal antibody against TRAF5.…
Ver producto