Human Trace Amine Associated Receptor 2 (TAAR2) Protein
1872€ (1 mg)
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name
Human Trace Amine Associated Receptor 2 (TAAR2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx655277
tested applications
WB, SDS-PAGE
Description
Human Trace Amine Associated Receptor 2 (TAAR2) Protein is a Recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Trace Amine Associated Receptor 2 (TAAR2) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Please enquire. Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 1 mg |
| Size 2 | 5 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 1-2 months. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | TAAR2,GPR58,taR-2,GPR58,G protein-coupled receptor 58,trace amine receptor 2,trace amine associated receptor 2 (gene/pseudogene) |
| Background | Protein TAAR2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
TAAR2 is another member of the trace amine-associated receptor family, closely related to TAAR1. It is activated by trace amines like phenylethylamine and other endogenous amines. TAAR2 is expressed in the brain, particularly in regions involved in olfaction, limbic functions, and mood regulation. Similar to TAAR1, TAAR2 couples to Gi proteins and modulates the release of neurotransmitters such as dopamine, serotonin, and norepinephrine, influencing neuronal activity and emotional states. While its exact physiological role is not as well characterized as TAAR1, TAAR2 is believed to play a role in the modulation of mood and sensory processing. It is involved in regulating behaviors associated with anxiety, arousal, and stress responses. Dysregulation of TAAR2 signaling is thought to be involved in neuropsychiatric disorders such as anxiety and depression, and it may contribute to the development of conditions like schizophrenia. Research into TAAR2 offers new potential avenues for the development of novel treatments for mood disorders and neuropsychiatric conditions.
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