Human Toll Like Receptor 1 (TLR1) ELISA Kit
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935106861
info@markelab.com
Precio
611€ (96 tests)
Elisa kits for TLR1
proveedor
Abbexareference
abx570435Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Toll Like Receptor 1 (TLR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Toll Like Receptor 1 (TLR1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Toll-like receptor 1 (TLR1) is a member of the toll-like receptor (TLR) family, a critical component of the innate immune system that detects and responds to pathogens through pattern recognition. TLRs are integral to recognizing pathogen-associated molecular patterns (PAMPs), which are conserved molecular structures in microbes, such as bacterial cell wall components. TLR1, in particular, functions predominantly as a co-receptor with TLR2 and recognizes lipoproteins and lipopeptides derived from bacterial membranes. By binding these ligands, TLR1 initiates intracellular signaling pathways that activate pro-inflammatory cytokine production and immune cell recruitment, key processes for mounting an immune response against infection. TLR1 is primarily expressed on immune cells like monocytes, macrophages, dendritic cells, and neutrophils, and is involved in host defense against bacterial, fungal, and some viral pathogens. Its role in immune responses makes TLR1 a valuable focus for understanding immune signaling pathways and developing potential treatments for infections, inflammatory diseases, and cancers.
Características del producto
category
ELISA Kits
immunogen target
Toll Like Receptor 1 (TLR1)
reactivity
Human
test range
0.312 ng/ml - 20 ng/ml
sensitivity
0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
Toll-like receptor 1,TIL,CD281,rsc786,TIL. LPRS5,Toll/interleukin-1 receptor-like protein
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TLR1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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