Human TNFRSF1A Associated Via Death Domain Protein (TRADD) Protein

Este producto es parte de TRADD - TNFRSF1A associated via death domain
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221€ (10 µg)

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935106861
info@markelab.com
name
Human TNFRSF1A Associated Via Death Domain Protein (TRADD) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069351
tested applications
WB, SDS-PAGE

Description

Recombinant TNFRSF1A Associated Via Death Domain Protein (TRADD) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
TNFRSF1A Associated Via Death Domain Protein (TRADD)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 30.2 kDa  Observed MW (SDS-PAGE): 32 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Met61-Leu297
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 97%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01%Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q15628
Alias
NFRSF1A associated via death domain,TRADD
Background
Protein TRADD
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

TNFRSF1A Associated Via Death Domain (TRADD) is an adaptor protein critical for tumor necrosis factor (TNF)-mediated signaling. It acts as a central platform for assembling signaling complexes upon TNF receptor 1 (TNFR1) activation. TRADD mediates divergent pathways leading to apoptosis, necroptosis, or NF-κB activation, depending on the recruited proteins. It plays a pivotal role in immune responses, inflammation, and cell death regulation. Aberrations in TRADD function are linked to immune dysregulation, chronic inflammation, and cancer. Its dual role in promoting cell survival and death makes it a crucial target for therapeutic strategies.

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