The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A(By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Primary Antibodies
polyclonal
human,mouse,rat
TNFRSF1A-associated via death domain
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IHC
34 kDa, 27 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:200 - 1:2000; IHC: 1:50 - 1:500
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
TRADD
NFRSF1A associated via death domain,TRADD
This product is for research use only.
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A...
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Ver másThe nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A...
Precio a consultar
Ver másTRADD Antibody is a Rabbit Polyclonal antibody against TRADD. The protein encoded by this gene is a death domain contain...
175€ (20 µl)
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