Human TNF Receptor Associated Factor 5 (TRAF5) CLIA Kit
845€ (96 tests)
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name
Human TNF Receptor Associated Factor 5 (TRAF5) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx495284
tested applications
CLIA
Description
Human TNF Receptor Associated Factor 5 (TRAF5) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | TNF Receptor Associated Factor 5 (TRAF5) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.064 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | TRAF-5,TRAF5, MGC:39780, RNF84, TNF receptor associated factor 5 |
| Background | CLIA Kits TRAF5 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
TRAF5 is a signaling adaptor protein that mediates pathways downstream of TNF receptors (TNFR), CD40, and BAFF-R, activating NF-κB and JNK to regulate inflammation, immune cell activation, and survival. TRAF5 plays a critical role in adaptive immune responses, particularly in T and B cell activation, cytokine production, and lymphoid tissue development. It works redundantly with TRAF2 to promote canonical NF-κB activation, ensuring appropriate immune responses to inflammatory and survival signals. TRAF5 is widely expressed in immune cells and epithelial tissues, where it supports cellular signaling during infections and tissue repair. Dysregulation of TRAF5 contributes to autoimmune diseases and inflammatory conditions, where altered NF-κB signaling enhances cytokine production and immune cell proliferation. Knockout studies reveal defects in lymphocyte activation, impaired cytokine signaling, and altered immune responses, highlighting its importance in immune regulation and inflammatory signaling.
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