Human Thrombopoietin Receptor / CD110 (MPL) CLIA Kit

Este producto es parte de MPL - thrombopoietin receptor
Human Thrombopoietin Receptor / CD110 (MPL) CLIA Kit
845€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Human Thrombopoietin Receptor / CD110 (MPL) CLIA Kit
Category
CLIA Kits
Provider
Abbexa
Reference
abx496583
Tested Applications
CLIA

Description

Human Myeloproliferative Leukemia Virus Oncogene (MPL) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
CLIA Kits
Immunogen Target
Thrombopoietin Receptor / CD110 (MPL)
Reactivity
Human
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.312 ng/ml - 20 ng/ml
Sensitivity
< 0.113 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard: Lyophilized
Tested Applications
CLIA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-20 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P40238
Gene ID
4352
OMIM
159530
Alias
MPL proto-oncogene, MPLV,TPOR,C-MPL,CD110,THPOR,THCYT2,PO-R,Myeloproliferative leukemia protein,Proto-oncogene c-Mpl
Background
CLIA Kits MPL
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES.  The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.  Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

MPL, also known as the thrombopoietin receptor, is a critical component in hematopoiesis, particularly for the regulation and production of platelets. It is the cellular receptor for thrombopoietin (TPO), a hormone produced primarily by the liver that promotes the proliferation and maturation of megakaryocytes, the precursors to platelets. MPL is a member of the type I cytokine receptor family and is essential for maintaining platelet counts within physiological ranges. Its activity regulates not only the production of platelets but also has implications in stem cell maintenance and self-renewal within the hematopoietic system. MPL is encoded by the MPL gene located on chromosome 1 (1p34) in humans. Mutations in this gene are associated with various myeloproliferative disorders and hematological diseases, including essential thrombocythemia, primary myelofibrosis, and certain leukemias. Due to its central role in platelet production and stem cell maintenance, MPL is a significant focus of research for understanding hematopoietic disorders and developing targeted therapies.

Productos relacionados

abx011224

Thrombopoietin Receptor / CD110 (MPL) Antibody

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immorta…

Ver producto
abx068134

Human Thrombopoietin Receptor / CD110 (MPL) Protein

Human Thrombopoietin Receptor / CD110 (MPL) is a recombinant Human protein expressed in E. coli.…

Ver producto
abx068135

Mouse Thrombopoietin Receptor / CD110 (MPL) Protein

Mouse Thrombopoietin Receptor / CD110 (MPL) is a recombinant Mouse protein expressed in E. coli.…

Ver producto