Human Tachykinin Receptor 3 (TACR3) ELISA Kit

Este producto es parte de TACR - Tachykinin Receptor
Human Tachykinin Receptor 3 (TACR3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

585€ (96 tests)

Elisa kits for TACR3

proveedor

Abbexa

reference

abx251003

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Tachykinin Receptor 3 (TACR3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Tachykinin Receptor 3 (TACR3) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

TACR3, also known as NK3R, is a G protein-coupled receptor activated by neurokinin B (NKB), a neuropeptide involved in regulating multiple physiological processes. TACR3 primarily couples to Gq proteins, stimulating phospholipase C (PLC), increasing intracellular calcium, and modulating cell signaling. It is predominantly expressed in the central nervous system (CNS), particularly in regions involved in regulating reproductive functions and controlling circadian rhythms. TACR3 plays a critical role in regulating the hypothalamic-pituitary-gonadal axis, influencing reproductive hormone release, and modulating sexual behavior. In addition, it is involved in controlling mood and anxiety by regulating neurogenic inflammation. Dysregulation of TACR3 signaling has been linked to conditions such as infertility, mood disorders, and certain cancers. Targeting TACR3 with antagonists offers potential therapeutic benefits in treating disorders related to reproductive function, anxiety, and neurogenic inflammation.

Características del producto

category

ELISA Kits


immunogen target

Tachykinin Receptor 3 (TACR3)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

0.1 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

TACR3,Neurokinin B receptor,neurokinin beta receptor,Nmkr,Tac3r,neuromedin K receptor,NK-3 receptor,SP-N receptor,HH11,NK-3R,NK3,NK3R,NKR,TAC3R,TAC3RL


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

TACR3


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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