Human Synemin (SYNM) ELISA Kit
715€ (96 tests)
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Name
Human Synemin (SYNM) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx585087
Tested Applications
ELISA
Description
Human Synemin (SYNM) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human SYNM concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Synemin (SYNM) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.07 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O15061 |
| Gene ID | 23336 |
| OMIM | 606087 |
| Alias | DMN,SYN,Desmuslin |
| Background | Elisa Kits for: SYNM |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
Synemin (SYNM) is a protein that plays a key role in maintaining the structural integrity of cells, particularly in muscle and neuronal tissues SYNM is involved in linking the intermediate filaments of the cytoskeleton to other cell structures such as the plasma membrane and actin filaments, contributing to the maintenance of cell shape and mechanical strength In muscle cells, synemin is particularly important for the structural organization of the sarcomere, the basic contractile unit of muscle fibers It also plays a role in cellular signaling and the regulation of growth and differentiation Synemin has been linked to diseases involving defects in the cytoskeleton, such as muscular dystrophies, where its dysfunction leads to impaired cell stability and muscle weakness Additionally, synemin is involved in the regulation of synaptic function and neuronal signaling, highlighting its importance in both muscle and nerve cell health Understanding synemin’s role in cell function and its association with muscle and neurological diseases provides potential insights into therapies for these conditions
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