Family main features
Synemin is an intermediate filament (IF) protein that plays a crucial role in maintaining the structural integrity and function of various cell types, particularly in muscle and neuronal cells. It is encoded by the SYNM gene and is highly conserved across species, reflecting its fundamental role in cellular architecture. Synemin integrates with other cytoskeletal proteins, contributing to the mechanical resilience and signaling pathways of cells. It was first identified in the context of muscle cells, where it associates with other intermediate filaments like desmin, vimentin, and nestin.
Molecular Weight: Approximately 180-230 kDa, depending on the isoform.
Synemin is classified as a member of the intermediate filament family of proteins.
Isoforms:
Synemin is a vital intermediate filament protein that ensures the structural integrity and functionality of muscle and neural cells. Through its multiple isoforms, synemin integrates into the cytoskeletal network, facilitating cell stability, signal transduction, and migration. It has significant implications in muscle and neurological disorders, as well as cancer, highlighting its importance in maintaining cellular homeostasis and its potential as a therapeutic target.
synemin (SYNM)
DMN,SYN,Desmuslin
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (ELISA Kits, Primary Antibodies) relacionados con SYNM - synemin
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 8 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | SYNM | abx585087 | Human Synemin (SYNM) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.07 ng/ml | 687.5 | 96 tests | O15061 | RUO |
Abbexa | SYNM | abx548177 | Mouse Synemin (SYNM) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.04 ng/ml | 687.5 | 96 tests | Q70IV5 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | SYNM | FNab08440 | anti- SYNM antibody | human | polyclonal | Rabbit | synemin, intermediate filament protein | IgG | Unconjugated | ELISA, WB, IHC, IF | 100µg | O15061 | RUO | |
Abbexa | SYNM | abx238440 | Synemin (SYNM) Antibody | Human | Polyclonal | Rabbit | Synemin (SYNM) | Unconjugated | ELISA, WB, IHC, IF/ICC | 350 | 100 µg | O15061 | RUO | |
Abbexa | SYNM | abx333909 | Synemin (SYNM) Antibody | Human | Polyclonal | Rabbit | Synemin (SYNM) | Unconjugated | ELISA, IHC, IF/ICC | 162.5 | 20 µg | O15061 | RUO | |
Abbexa | SYNM | abx337861 | Synemin (SYNM) Antibody (Biotin) | Human | Polyclonal | Rabbit | Synemin (SYNM) | Biotin | ELISA | 162.5 | 20 µg | O15061 | RUO | |
Abbexa | SYNM | abx337860 | Synemin (SYNM) Antibody (FITC) | Human | Polyclonal | Rabbit | Synemin (SYNM) | FITC | 162.5 | 20 µg | O15061 | RUO | ||
Abbexa | SYNM | abx337859 | Synemin (SYNM) Antibody (HRP) | Human | Polyclonal | Rabbit | Synemin (SYNM) | HRP | ELISA | 162.5 | 20 µg | O15061 | RUO |
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