Human Syndecan-1 (SDC1) Protein
221€ (10 µg)
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935106861
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name
Human Syndecan-1 (SDC1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168119
tested applications
WB, SDS-PAGE
Description
Human Syndecan-1 (SDC1) Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Syndecan-1 (SDC1) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Gln23-Leu253 Tag: N-terminal His tag and GST tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 56.2 kDa Observed MW (SDS-PAGE): 75 kDa Possible reasons why the actual band size differs from the predicted band size: 1. Splice variants. Alternative splicing may create different sized proteins from the same gene. 2. Relative charge. The composition of amino acids may affect the charge of the protein. 3. Post-translational modification. Phosphorylation, glycoslyation, methylation etc. may affect the band size. 4. Post-translational cleavage. Many proteins are synthesised as pro-proteins, and then cleaved to give the active form. 5. Polymerisation of the target protein. Dimerisation, multimerisation etc. will increase the band size observed. |
| Expression | Recombinant |
| Purity | > 80% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | P18827 |
| Gene ID | 6382 |
| Alias | SDC,CD138,SYND1 |
| Background | Protein SDC1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in ddH2O to a concentration between 0.1-0.5 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 80 µg/ml |
Descripción
Syndecan-1 (SDC1), a cell surface heparan sulfate proteoglycan, is encoded by the SDC1 gene and is part of the syndecan family, which includes four distinct proteoglycans (syndecans 1-4). These proteoglycans are integral to cell surface structure, functioning in cellular communication, adhesion, migration, and the regulation of growth factors. Syndecan-1 is expressed on various cell types, including epithelial cells, B cells, and plasma cells, where it plays crucial roles in cell-matrix interactions and intracellular signaling. Additionally, SDC1 is dynamically regulated in response to tissue injury and inflammation, underscoring its significance in wound healing, inflammation, and cancer progression.
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