Human Steroid hormone receptor ERR1 (ESRRA) ELISA Kit

Este producto es parte de ESRR - estrogen related receptor
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Steroid hormone receptor ERR1 (ESRRA) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx522330
tested applications
ELISA

Description

Human Steroid hormone receptor ERR1 (ESRRA) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Steroid hormone receptor ERR1 (ESRRA) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetSteroid hormone receptor ERR1 (ESRRA)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Test Range0.156 ng/ml - 10 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-15 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDP11474
Gene ID2101
OMIM601998
AliasERR1,ERRa,ESRL1,NR3B1,ERRalpha,Steroid hormone receptor ERR1,Estrogen receptor-like 1,Nuclear receptor subfamily 3 group B member 1
BackgroundElisa kits for ESRRA
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Estrogen related receptor alpha (ESRRA) is a nuclear receptor that is involved in regulating energy metabolism, mitochondrial function, and cellular differentiation ESRRA, also known as ERRα, is activated in response to metabolic signals and plays a central role in regulating the expression of genes involved in oxidative metabolism, fatty acid oxidation, and glucose homeostasis It is highly expressed in tissues with high metabolic activity, such as the heart, liver, and muscle, where it helps maintain cellular energy balance by modulating mitochondrial biogenesis and function ESRRA is also important for maintaining normal brain function, bone homeostasis, and cardiovascular health Dysregulation of ESRRA has been linked to metabolic disorders such as obesity, type 2 diabetes, and cardiovascular diseases, as well as certain types of cancer where altered mitochondrial function and energy metabolism contribute to tumor growth ESRRA represents a potential target for therapies aimed at enhancing metabolic health and preventing diseases related to mitochondrial dysfunction

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