Human SSTR1 (Somatostatin Receptor 1) ELISA Kit

Este producto es parte de SSTR - Somatostatin Receptor
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935106861
info@markelab.com
name
Human SSTR1 (Somatostatin Receptor 1) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH3821
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
P30872
Alias
SSTR1,SRIF-2,SS1R,SRIF-2,SS-1-R,SS1-R,SST1
Background
Elisa kits for SSTR1
Status
RUO

SSTR1 is a G protein-coupled receptor (GPCR) that binds somatostatin, a peptide hormone that inhibits the release of various other hormones, including growth hormone, insulin, and glucagon. SSTR1 is predominantly expressed in the brain, pancreas, and gastrointestinal tract. It primarily couples to Gi proteins, inhibiting adenylate cyclase activity and reducing cAMP levels, which leads to the suppression of hormone secretion and modulation of neurotransmitter release. In the central nervous system, SSTR1 regulates neurotransmission and has a role in inhibiting secretion of growth hormone from the pituitary. Dysregulation of SSTR1 signaling is implicated in disorders like acromegaly, diabetes, and certain neuroendocrine tumors, where excessive hormone secretion or abnormal growth occurs. SSTR1 agonists, such as octreotide, are used therapeutically to treat conditions such as acromegaly and neuroendocrine tumors by inhibiting growth hormone and other secretions.

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