Human Somatostatin Receptor 1 (SSTR1) ELISA Kit

Este producto es parte de SSTR - Somatostatin Receptor
Human Somatostatin Receptor 1 (SSTR1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

513.5€ (96 tests)

Elisa kits for SSTR1

proveedor

Abbexa

reference

abx253214

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Somatostatin Receptor 1 (SSTR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human SSTR1 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

SSTR1 is a G protein-coupled receptor (GPCR) that binds somatostatin, a peptide hormone that inhibits the release of various other hormones, including growth hormone, insulin, and glucagon. SSTR1 is predominantly expressed in the brain, pancreas, and gastrointestinal tract. It primarily couples to Gi proteins, inhibiting adenylate cyclase activity and reducing cAMP levels, which leads to the suppression of hormone secretion and modulation of neurotransmitter release. In the central nervous system, SSTR1 regulates neurotransmission and has a role in inhibiting secretion of growth hormone from the pituitary. Dysregulation of SSTR1 signaling is implicated in disorders like acromegaly, diabetes, and certain neuroendocrine tumors, where excessive hormone secretion or abnormal growth occurs. SSTR1 agonists, such as octreotide, are used therapeutically to treat conditions such as acromegaly and neuroendocrine tumors by inhibiting growth hormone and other secretions.

Características del producto

category

ELISA Kits


immunogen target

Somatostatin Receptor 1 (SSTR1)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

0.1 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

SSTR1,SRIF-2,SS1R,SRIF-2,SS-1-R,SS1-R,SST1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

SSTR1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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