Human Sialic Acid-Binding Ig-Like Lectin 9 (SIGLEC9) Protein
221€ (10 µg)
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935106861
info@markelab.com
name
Human Sialic Acid-Binding Ig-Like Lectin 9 (SIGLEC9) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069074
tested applications
WB, SDS-PAGE
Description
Recombinant Sialic Acid-Binding Ig-Like Lectin 9 (SIGLEC9) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Sialic Acid-Binding Ig-Like Lectin 9 (SIGLEC9) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 19.5 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu23-Leu142 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y336 |
| Alias | CD329,CDw329,FOAP-9,siglec-9,OBBP-LIKE |
| Background | Protein SIGLEC9 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
SIGLEC9 is widely expressed on neutrophils, monocytes, and subsets of T cells. It binds preferentially to α2-3-linked sialic acids on glycoproteins and glycolipids. SIGLEC9 plays a dual role in modulating immune responses by dampening excessive inflammation through its ITIM domains and enhancing the clearance of apoptotic cells by phagocytes. This protein is critical in host-pathogen interactions, as many pathogens exploit sialic acid-binding properties to evade immune detection. SIGLEC9 is being explored as a target in inflammatory diseases and cancer due to its role in modulating immune activation and resolution.
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