Human Sialic Acid-Binding Ig-Like Lectin 9 (SIGLEC9) Protein

Este producto es parte de SIGLEC - sialic acid binding Ig like lectin
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221€ (10 µg)

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935106861
info@markelab.com
name
Human Sialic Acid-Binding Ig-Like Lectin 9 (SIGLEC9) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069074
tested applications
WB, SDS-PAGE

Description

Recombinant Sialic Acid-Binding Ig-Like Lectin 9 (SIGLEC9) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Sialic Acid-Binding Ig-Like Lectin 9 (SIGLEC9)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 19.5 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Leu23-Leu142
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9Y336
Alias
CD329,CDw329,FOAP-9,siglec-9,OBBP-LIKE
Background
Protein SIGLEC9
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

SIGLEC9 is widely expressed on neutrophils, monocytes, and subsets of T cells. It binds preferentially to α2-3-linked sialic acids on glycoproteins and glycolipids. SIGLEC9 plays a dual role in modulating immune responses by dampening excessive inflammation through its ITIM domains and enhancing the clearance of apoptotic cells by phagocytes. This protein is critical in host-pathogen interactions, as many pathogens exploit sialic acid-binding properties to evade immune detection. SIGLEC9 is being explored as a target in inflammatory diseases and cancer due to its role in modulating immune activation and resolution.

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Recombinant Sialic Acid-Binding Ig-Like Lectin 9 (SIGLEC9) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

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