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Human Sialic Acid Binding Ig Like Lectin 8 (SIGLEC8) CLIA Kit
Pida mas información
935106861
info@markelab.com
Precio
812.5€ (96 tests)
CLIA Kits SIGLEC8
proveedor
Abbexareference
abx493077Tested Applications
CLIAreactivity
Humanstatus
RUOclonality
Descripción
Human Sialic Acid Binding Ig Like Lectin 8 (SIGLEC8) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Cell lysates.
Human Sialic Acid Binding Ig Like Lectin 8 (SIGLEC8) CLIA Kit is a Sandwich CLIA Kit for use with Cell lysates.
Background
SIGLEC8 is an inhibitory receptor expressed mainly on eosinophils, mast cells, and basophils. It binds selectively to 6′-sulfated sialyl Lewis X and related glycan ligands, regulating inflammatory responses in allergic diseases. Activation of SIGLEC8 leads to eosinophil apoptosis and inhibition of mast cell degranulation, making it an attractive therapeutic target for asthma and eosinophilic disorders. Its function is mediated through ITIMs, which dampen cell activation pathways. SIGLEC8 is also implicated in maintaining immune homeostasis in tissues and resolving allergic inflammation.
Características del producto
category
CLIA Kits
immunogen target
Sialic Acid Binding Ig Like Lectin 8 (SIGLEC8)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.058 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Chemiluminescent
sample type
Cell lysates.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
SAF2,SIGLEC-8,SIGLEC8L,Sialoadhesin family member 2
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
SIGLEC8
dry ice
No
note
El rango y la sensibilidad pueden variar. Le recomendamos contactar con nosotros a fin de obtener la última información sobre posibles actualizaciones, que no estén representadas en este catalogo. Si necesita un rango específico, contáctenos y trataremos de ayudarle. Consulte sobre posible información que pueda ayudarle a elegir la dilución apropiada para sus muestras. Los kits CLIA están optimizados para la detección de muestras nativas, las proteínas recombinantes, pueden resultar problemáticas a causa de diferencias en la secuencia o cambios en la estructura terciaria.
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