Human Sialic acid-binding Ig-like lectin 14 (SIGLEC14) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits SIGLEC14
proveedor
Abbexareference
abx545882Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Sialic acid-binding Ig-like lectin 14 (SIGLEC14) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Sialic acid-binding Ig-like lectin 14 (SIGLEC14) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Background
SIGLEC14 is a member of the Siglec family expressed on myeloid cells, including monocytes and neutrophils. It is paired with SIGLEC5, with which it shares high sequence similarity, forming an activating counterpart to the inhibitory SIGLEC5. SIGLEC14 binds to sialic acid-containing glycans on pathogens and self-tissues, triggering pro-inflammatory responses. This protein has been implicated in innate immune activation, particularly in recognizing bacterial infections. SIGLEC14 also plays a role in the modulation of immune responses, balancing activation and tolerance. Genetic variations in SIGLEC14 can result in a fusion with SIGLEC5, altering its expression and immune function.
Características del producto
category
ELISA Kits
immunogen target
Sialic acid-binding Ig-like lectin 14 (SIGLEC14)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
Siglec-14
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
SIGLEC14
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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