Human Serpin B5 (SERPINB5) Protein

Este producto es parte de SERPINB5 - serpin family B member 5
Product Graph
234€ (10 µg)

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935106861
info@markelab.com
name
Human Serpin B5 (SERPINB5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167006
tested applications
WB, SDS-PAGE

Description

Mammary Serine Protease Inhibitor Protein is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Serpin B5 (SERPINB5)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 45.8 kDa  Observed MW (SDS-PAGE): 46 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Met1-Pro375
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 97%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
PI5,maspin,Serpin B5,Peptidase inhibitor 5
Background
Protein SERPINB5
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

SERPINB5, also known as maspin (mammary serine protease inhibitor), is a member of the serpin (serine protease inhibitor) superfamily. Unlike many other serpins that function as protease inhibitors, SERPINB5 is unique in that it does not inhibit protease activity. Discovered in the early 1990s, SERPINB5 has since been the subject of extensive research due to its involvement in various cellular processes and its implications in cancer biology. This protein is encoded by the SERPINB5 gene located on chromosome 18q21.3, a region that has been associated with several types of cancer, particularly breast cancer. SERPINB5 is primarily expressed in epithelial cells and has been implicated in processes such as cell adhesion, migration, and apoptosis.

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