Human Semaphorin 3A (SEMA3A) CLIA Kit

Este producto es parte de SEMA3 - semaphorin 3
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643.5€ (96 tests)

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935106861
info@markelab.com
name
Human Semaphorin 3A (SEMA3A) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx197668
tested applications
CLIA

Description

Human Semaphorin 3A (SEMA3A) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Semaphorin 3A (SEMA3A).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryCLIA Kits
Immunogen TargetSemaphorin 3A (SEMA3A)
ReactivityHuman
Detection MethodChemiluminescent
Assay DataQuantitative
Assay TypeSandwich
Test Range31.2 pg/ml - 2000 pg/ml
Sensitivity18.8 pg/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsCLIA
Sample TypeSerum, plasma and other biological fluids.
AvailabilityShipped within 5-12 working days.
Storage Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
AliasHH16,SemD,COLL1,SEMA1,SEMAD,SEMAL,coll-1,Hsema-I,SEMAIII,Hsema-III,Semaphorin III,Semaphorin-3A
BackgroundCLIA Kits SEMA3A
StatusRUO
NoteThe validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

SEMA3A (Semaphorin 3A) is a member of the class 3 semaphorin family, functioning as a guidance cue in axonal development and neuronal migration. It binds to neuropilin-1 (NRP1) and plexin receptors to mediate repulsive signaling in neural networks, playing a critical role in synapse formation and maintenance. Beyond neural contexts, SEMA3A also influences angiogenesis, immune cell regulation, and cancer progression, with high relevance in tumor microenvironments where it modulates vascular growth and cell invasion. Its therapeutic potential lies in targeting its pathways for diseases involving aberrant cell migration and angiogenesis, including cancer and vascular disorders.

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