Human sCD14 (Soluble Cluster of Differentiation14) ELISA Kit

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name
Human sCD14 (Soluble Cluster of Differentiation14) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH3747
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Reactivity | Human |
Detection Method | Colorimetric |
Assay Data | 4 hours |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 0.156-10ng/ml |
Sensitivity | 0.094ng/ml |
Size 1 | 96T |
Tested Applications | ELISA |
Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 12 months |
UniProt ID | P08571 |
Alias | sCD14, Soluble Cluster of Differentiation14, CD14, CD14 antigen, CD14 molecule, monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein |
Background | Elisa kits for sCD14 |
Status | RUO |
Soluble Cluster of Differentiation 14 (sCD14) is a crucial glycoprotein primarily expressed on the surface of monocytes, macrophages, and neutrophils, as well as existing in a soluble form (sCD14) in circulation. This molecule acts as a co-receptor for the detection of bacterial lipopolysaccharides (LPS), a component of Gram-negative bacterial cell walls, in conjunction with Toll-like receptor 4 (TLR4) and MD-2. CD14 is pivotal in innate immunity, where it aids in the recognition of pathogens and triggers immune responses. Soluble CD14 is particularly significant in tissues and cells lacking membrane-bound CD14, enabling a broader immune response. Dysregulation of CD14 levels is linked to various inflammatory and infectious diseases, including sepsis, atherosclerosis, and autoimmune conditions. As a biomarker, soluble CD14 is used in research and clinical diagnostics to assess inflammation and immune activation. It plays an essential role in understanding host-pathogen interactions and inflammatory pathways.
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