Human Roundabout Homolog 2 (ROBO2) Protein
1079€ (100 µg)
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935106861
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name
Human Roundabout Homolog 2 (ROBO2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx692548
tested applications
SDS-PAGE
Description
Human ROBO2 Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the human ROBO2 (Q9HCK4-1) (Met1-Pro859) was expressed with a polyhistidine tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Roundabout Homolog 2 (ROBO2) |
| Host | HEK293 cells |
| Origin | Human |
| Observed MW | Molecular Weight: 94.2 kDa Sequence Fragment: Met1-Pro859 Tag: C-terminal His tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9HCK4-1 |
| Gene ID | 6092 |
| OMIM | 602431 |
| Alias | NORS,NYS8,SAX3,CPHD8,DUTT1,Deleted in U twenty twenty,H-Robo-1,Roundabout homolog 1 |
| Background | Protein ROBO2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ROBO2 (Roundabout Guidance Receptor 2) shares structural and functional similarities with ROBO1, playing a complementary role in neural development and guidance. It ensures the proper wiring of axonal tracts and is crucial for midline crossing of axons in the central nervous system. Beyond neural functions, ROBO2 is involved in kidney morphogenesis and epithelial tissue organization. It participates in Slit-dependent signaling pathways, which regulate cellular adhesion and migration. Aberrations in ROBO2 expression or function have been linked to congenital kidney abnormalities and developmental disorders, further underscoring its critical role in maintaining developmental and tissue-specific integrity.
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