Human Rhodopsin (RHO) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for RHO
proveedor
Abbexareference
abx152960Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Rhodopsin (RHO) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Rhodopsin concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Rhodopsin (RHO)
Background
Rhodopsin (RHO) is a light-sensitive G protein-coupled receptor found in the rod cells of the retina, which plays a crucial role in vision, especially in low-light conditions. It is composed of the protein opsin and a retinal chromophore. When light hits rhodopsin, the retinal undergoes a conformational change, activating the opsin and initiating a signaling cascade that results in hyperpolarization of the rod cell and the transmission of visual signals to the brain. Rhodopsin is highly sensitive to light, making it essential for scotopic vision, or vision in dim light. Mutations in the RHO gene can lead to various retinal diseases, including retinitis pigmentosa, which causes progressive vision loss and, eventually, blindness. Research into rhodopsin and its mechanisms is important for understanding retinal diseases and developing potential therapies to treat them, including gene therapies and pharmacological interventions to restore or protect vision.
Características del producto
category
ELISA Kits
immunogen target
Rhodopsin (RHO)
reactivity
Human
test range
1.56 ng/ml - 100 ng/ml
sensitivity
< 0.59 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
RHO,RP4,OPN2,CSNBAD1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
RHO
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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