Human Rhodopsin (RHO) CLIA Kit
845€ (96 tests)
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name
Human Rhodopsin (RHO) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx493897
tested applications
CLIA
Description
Human Rhodopsin (RHO) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Rhodopsin (RHO) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 1.56 ng/ml - 100 ng/ml |
| Sensitivity | < 0.58 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | RHO,RP4,OPN2,CSNBAD1 |
| Background | CLIA Kits RHO |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Rhodopsin (RHO) is a light-sensitive G protein-coupled receptor found in the rod cells of the retina, which plays a crucial role in vision, especially in low-light conditions. It is composed of the protein opsin and a retinal chromophore. When light hits rhodopsin, the retinal undergoes a conformational change, activating the opsin and initiating a signaling cascade that results in hyperpolarization of the rod cell and the transmission of visual signals to the brain. Rhodopsin is highly sensitive to light, making it essential for scotopic vision, or vision in dim light. Mutations in the RHO gene can lead to various retinal diseases, including retinitis pigmentosa, which causes progressive vision loss and, eventually, blindness. Research into rhodopsin and its mechanisms is important for understanding retinal diseases and developing potential therapies to treat them, including gene therapies and pharmacological interventions to restore or protect vision.
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