Human Retinoid X Receptor Gamma (RXRg) Protein
221€ (10 µg)
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935106861
info@markelab.com
name
Human Retinoid X Receptor Gamma (RXRg) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650546
tested applications
WB, SDS-PAGE
Description
Human RXRg Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Retinoid X Receptor Gamma (RXRg) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 26.0 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Pro12-Ala220 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P48443 |
| Alias | RXRC,NR2B3,RXRgamma,RXR-gamma,Retinoic acid receptor RXR-gamma,Retinoid X receptor gamma,Nuclear receptor subfamily 2 group B member 3 |
| Background | Protein RXRG |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Retinoid X receptor gamma (RXRG) is another retinoid X receptor involved in regulating gene expression and cellular processes in response to retinoids RXRG shares many of the functions of RXRA and RXRB but is particularly involved in regulating genes related to energy metabolism, cell differentiation, and inflammation RXRG plays a key role in the regulation of lipid metabolism, glucose homeostasis, and the response to oxidative stress It is expressed in tissues such as adipose tissue, skeletal muscle, and the liver, where it helps control the transcription of genes involved in fat storage and energy utilization RXRG is also involved in regulating immune function and inflammation, particularly in the context of autoimmune diseases and inflammatory disorders Dysregulation of RXRG is associated with metabolic diseases like obesity, diabetes, and fatty liver disease, as well as certain cancers Its involvement in immune regulation and metabolic pathways makes RXRG a critical factor in maintaining overall homeostasis RXRG represents a potential therapeutic target for treating metabolic and inflammatory diseases, as well as cancers, by modulating its role in lipid metabolism, inflammation, and cell differentiation
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