Human Relaxin/Insulin Like Family Peptide Receptor 2 (RXFP2) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits RXFP2
proveedor
Abbexareference
abx385364Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Relaxin/Insulin Like Family Peptide Receptor 2 (RXFP2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human RXFP2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
RXFP2 is another member of the relaxin/insulin-like family peptide receptors, activated by relaxin-2 and its analogs. RXFP2 primarily couples to Gs proteins, stimulating adenylate cyclase to increase cAMP levels and induce downstream effects such as smooth muscle relaxation, vasodilation, and remodeling of tissues. RXFP2 is expressed in various tissues, including the brain, reproductive system, and heart, where it is involved in regulating reproductive functions such as ovulation, pregnancy, and labor, as well as maintaining vascular tone. RXFP2 also plays a key role in modulating heart function by influencing cardiac remodeling, fibrosis, and endothelial function. Dysregulation of RXFP2 signaling has been implicated in cardiovascular diseases, infertility, and pregnancy complications. Targeting RXFP2 with agonists or antagonists holds promise for treating conditions such as heart failure, preterm labor, and fibrotic diseases by promoting tissue remodeling and vascular homeostasis.
Características del producto
category
ELISA Kits
immunogen target
Relaxin/Insulin Like Family Peptide Receptor 2 (RXFP2)
reactivity
Human
test range
0.313 ng/ml - 20 ng/ml
sensitivity
< 0.188 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
RXFP2,GPR106,RXFPR2,relaxin receptor 2,LGR8,INSL3 receptor,leucine-rich repeat-containing G protein-coupled receptor 8,relaxin/insulin like family peptide receptor 2,GREAT, INSL3R, LGR8, LGR8.1
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
RXFP2
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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