Human Relaxin/Insulin Like Family Peptide Receptor 2 (RXFP2) ELISA Kit

Este producto es parte de LGR - Leucine Rich Repeat Containing G Protein-Coupled Receptor
Human Relaxin/Insulin Like Family Peptide Receptor 2 (RXFP2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits RXFP2

proveedor

Abbexa

reference

abx385364

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Relaxin/Insulin Like Family Peptide Receptor 2 (RXFP2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human RXFP2 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

RXFP2 is another member of the relaxin/insulin-like family peptide receptors, activated by relaxin-2 and its analogs. RXFP2 primarily couples to Gs proteins, stimulating adenylate cyclase to increase cAMP levels and induce downstream effects such as smooth muscle relaxation, vasodilation, and remodeling of tissues. RXFP2 is expressed in various tissues, including the brain, reproductive system, and heart, where it is involved in regulating reproductive functions such as ovulation, pregnancy, and labor, as well as maintaining vascular tone. RXFP2 also plays a key role in modulating heart function by influencing cardiac remodeling, fibrosis, and endothelial function. Dysregulation of RXFP2 signaling has been implicated in cardiovascular diseases, infertility, and pregnancy complications. Targeting RXFP2 with agonists or antagonists holds promise for treating conditions such as heart failure, preterm labor, and fibrotic diseases by promoting tissue remodeling and vascular homeostasis.

Características del producto

category

ELISA Kits


immunogen target

Relaxin/Insulin Like Family Peptide Receptor 2 (RXFP2)


reactivity

Human


test range

0.313 ng/ml - 20 ng/ml


sensitivity

< 0.188 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

RXFP2,GPR106,RXFPR2,relaxin receptor 2,LGR8,INSL3 receptor,leucine-rich repeat-containing G protein-coupled receptor 8,relaxin/insulin like family peptide receptor 2,GREAT, INSL3R, LGR8, LGR8.1


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

RXFP2


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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