Human Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
546€ (96 tests)
Elisa kits for RXFP1
proveedor
Abbexareference
abx253121Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Relaxin/Insulin Like Family Peptide Receptor 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
RXFP1 is a G protein-coupled receptor activated by relaxin, a peptide hormone involved in reproductive, cardiovascular, and renal physiology. RXFP1 primarily couples to Gs proteins, stimulating adenylate cyclase and increasing intracellular cAMP levels, which in turn affects smooth muscle relaxation, vasodilation, and cell proliferation. RXFP1 is expressed in the reproductive tissues, kidneys, and blood vessels, where it plays a role in pregnancy, cardiac remodeling, and kidney function. During pregnancy, RXFP1 helps modulate uterine relaxation and cervical ripening. In cardiovascular health, RXFP1 is involved in regulating blood pressure and maintaining vascular integrity. Dysregulation of RXFP1 is linked to pregnancy complications, hypertension, and fibrosis. As a target for cardiovascular and renal diseases, RXFP1 receptor agonists are being explored for their potential in promoting tissue repair and reducing fibrosis, while antagonists could be used to modulate pregnancy-related vascular changes.
Características del producto
category
ELISA Kits
immunogen target
Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1)
reactivity
Human
test range
15.6 pg/ml - 1000 pg/ml
sensitivity
9.38 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
RXFP1,LGR7,RXFPR1,relaxin receptor 1,leucine-rich repeat-containing G-protein-coupled receptor 7,RX1,relaxin/insulin like family peptide receptor 1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
RXFP1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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