Human Relaxin-3 receptor 2 (RXFP4) ELISA Kit

Este producto es parte de LGR - Leucine Rich Repeat Containing G Protein-Coupled Receptor
Human Relaxin-3 receptor 2 (RXFP4) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for RXFP4

proveedor

Abbexa

reference

abx542655

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Relaxin-3 receptor 2 (RXFP4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Relaxin-3 receptor 2 (RXFP4) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

RXFP4, also known as the INSL5 receptor, is a G protein-coupled receptor activated by insulin-like peptide 5 (INSL5), a peptide hormone that plays a role in regulating gastrointestinal function, reproductive physiology, and metabolism. RXFP4 primarily couples to Gs proteins, increasing cAMP levels, and activating pathways involved in smooth muscle relaxation and hormone secretion. It is expressed in the gastrointestinal tract, pancreas, and reproductive organs, where it regulates processes such as intestinal motility, glucose homeostasis, and reproductive function. INSL5 and RXFP4 signaling is involved in the regulation of feeding behavior and insulin secretion. Dysregulation of RXFP4 signaling has been linked to metabolic disorders, such as obesity and type 2 diabetes, and gastrointestinal conditions, including irritable bowel syndrome (IBS). RXFP4 antagonists and agonists are being investigated for their potential therapeutic applications in treating metabolic diseases and gastrointestinal disorders.

Características del producto

category

ELISA Kits


immunogen target

Relaxin-3 receptor 2 (RXFP4)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

RXFP4,RLN3R2,GPCR142,INSL5 receptor,RXFPR4,G protein-coupled receptor 100,relaxin/insulin-like family peptide receptor 4,relaxin/insulin like family peptide receptor 4,GPR100


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

RXFP4


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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