Human Receptor-type tyrosine-protein phosphatase mu (PTPRM) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Receptor-type tyrosine-protein phosphatase mu (PTPRM) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx540755
tested applications
ELISA
Description
Human Receptor-type tyrosine-protein phosphatase mu (PTPRM) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Receptor-type tyrosine-protein phosphatase mu (PTPRM) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Receptor-type tyrosine-protein phosphatase mu (PTPRM) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P28827 |
| Gene ID | 5797 |
| OMIM | 176888 |
| Alias | RPTPM,RPTPU,PTPRL1,hR-PTPu,R-PTP-MU,Protein-tyrosine phosphatase mu,Receptor-type tyrosine-protein phosphatase mu |
| Background | Elisa kits for PTPRM |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PTPRM, also known as RPTPμ, is a receptor-like protein tyrosine phosphatase that regulates cell-cell adhesion, signaling, and growth suppression. Structurally, PTPRM contains extracellular Ig-like and fibronectin type III domains, a transmembrane domain, and two intracellular phosphatase domains. PTPRM mediates homophilic binding, meaning it interacts with other PTPRM molecules on adjacent cells to facilitate cell-cell adhesion. It plays essential roles in maintaining tissue architecture, especially in epithelial and endothelial cells. PTPRM interacts with cadherins and catenins to regulate cell adhesion and cytoskeletal organization. Loss or downregulation of PTPRM is associated with cancer progression and metastasis due to disrupted cell adhesion. Its regulatory role in neuronal guidance and tissue integrity also highlights its importance in development and cancer biology.
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