Human Receptor-type tyrosine-protein phosphatase H (PTPRH) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Receptor-type tyrosine-protein phosphatase H (PTPRH) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx540749
tested applications
ELISA
Description
Human Receptor-type tyrosine-protein phosphatase H (PTPRH) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Receptor-type tyrosine-protein phosphatase H (PTPRH) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Receptor-type tyrosine-protein phosphatase H (PTPRH) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9HD43 |
| Alias | SAP1,R-PTP-H,Stomach cancer-associated protein tyrosine phosphatase 1,Transmembrane-type protein-tyrosine phosphatase type H,Receptor-type tyrosine-protein phosphatase H |
| Background | Elisa kits for PTPRH |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PTPRH, also known as stomach cancer-associated protein tyrosine phosphatase-1 (SAP-1), is a receptor-like protein tyrosine phosphatase predominantly expressed in epithelial cells of the gastrointestinal tract. Structurally, PTPRH comprises an extracellular domain with multiple fibronectin type III repeats, a transmembrane region, and two intracellular phosphatase domains. PTPRH plays a role in epithelial cell signaling by regulating the activity of receptor tyrosine kinases, including EGFR (epidermal growth factor receptor). This regulation influences processes such as cell growth, differentiation, and migration. PTPRH is implicated in maintaining epithelial homeostasis and is overexpressed in gastrointestinal cancers, particularly gastric and colorectal cancers. Its dysregulation contributes to abnormal epithelial proliferation and cancer progression, making it a potential therapeutic target in oncology.
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