Human Receptor-type tyrosine-protein phosphatase H (PTPRH) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits PTPRH
proveedor
Abbexareference
abx540749Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Receptor-type tyrosine-protein phosphatase H (PTPRH) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Receptor-type tyrosine-protein phosphatase H (PTPRH) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
PTPRH, also known as stomach cancer-associated protein tyrosine phosphatase-1 (SAP-1), is a receptor-like protein tyrosine phosphatase predominantly expressed in epithelial cells of the gastrointestinal tract. Structurally, PTPRH comprises an extracellular domain with multiple fibronectin type III repeats, a transmembrane region, and two intracellular phosphatase domains. PTPRH plays a role in epithelial cell signaling by regulating the activity of receptor tyrosine kinases, including EGFR (epidermal growth factor receptor). This regulation influences processes such as cell growth, differentiation, and migration. PTPRH is implicated in maintaining epithelial homeostasis and is overexpressed in gastrointestinal cancers, particularly gastric and colorectal cancers. Its dysregulation contributes to abnormal epithelial proliferation and cancer progression, making it a potential therapeutic target in oncology.
Características del producto
category
ELISA Kits
immunogen target
Receptor-type tyrosine-protein phosphatase H (PTPRH)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
SAP1,R-PTP-H,Stomach cancer-associated protein tyrosine phosphatase 1,Transmembrane-type protein-tyrosine phosphatase type H,Receptor-type tyrosine-protein phosphatase H
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
PTPRH
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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